Rapamycin example data used for the vignette about binary control/treated data. The data was obtained from Piazza 2020 and corresponds to experiment 18. FKBP1A the rapamycin binding protein and 49 other randomly sampled proteins were used for this example dataset. Furthermore, only the DMSO control and the 10 uM condition were used.
A data frame containing peptide level data from a Spectronaut report.
Piazza, I., Beaton, N., Bruderer, R. et al. A machine learning-based chemoproteomic approach to identify drug targets and binding sites in complex proteomes. Nat Commun 11, 4200 (2020). https://doi.org/10.1038/s41467-020-18071-x